On June 7, the National Library of Medicine’s PubChem program gave a short (15 minute) webinar on its Laboratory Chemical Safety Summary data views. You can view it here and take a quick user survey to help us continue to improve this resource.
Information Flow in Environmental Health & Safety
At the Spring, 2017 ACS national meeting, the Divisions of Chemical Information and Chemical Health and Safety co-sponsored a program on Information Flow in Environmental Health and Safety. The symposia presented a variety of use cases for chemical information tools that range from lab-specific to very general. Links to the PDF versions of the presentations are provided below.
PubChem LCSS Update – March 2017
The PubChem database, hosted by the US National Library of Medicine, includes a wide variety of data on over 90 million chemical compounds. PubChem’s goal is to make this data accessible to chemists, chemical safety professionals, chemical educators and others working with laboratory chemicals. Data are reported from multiple sources, allowing users to compare and determine the best use of this data in their work. The data are also organized to facilitate downloading in a variety of formats as well via programmatic access for reuse in local software applications.
In addition to structural, physical and toxicological raw data, the PubChem collection includes chemical safety information from national and international agencies. For human browsers, this chemical safety information in PubChem is organized into a data view based on the Laboratory Chemical Safety Summary (LCSS) format described in “Prudent Practices in the Laboratory“. This LCSS view chemical and physical properties and safety information for compounds that have Globally Harmonized System designations publicly available. The number of records with this chemical safety information has increased from 3000 in 2015 to more than 103,000 today. LCSS data provided by PubChem are intended to support, but not replace, laboratory risk assessments, Safety Data Sheets and institutional guidance for safe laboratory practices and procedures.
Notably, the data compiled by PubChem includes safety information beyond that generally provided by Safety Data Sheets. This additional information is found in sources such as the NIOSH Pocket Guide, CAMEO and European Chemicals Agency, among others. There are also specific incompatible reactions reported from the Hazardous Substances Data Bank (HSDB), sourced from Sigma Aldrich Safety Center notes, the National Fire Protection Association Fire Protection Guide to Hazardous Materials, Sax’s Dangerous Properties of Industrial Materials, Bretherick’s Handbook of Reactive Chemical Hazards and others.
LCSS data can be viewed online, or downloaded either by individual compound or in bulk. In this way, PubChem information can be used to support electronic safety tools such as institutional chemical inventory management systems or laboratory-specific personal protective equipment guidelines. More information about this feature can be found here.
Traffic to the safety information in PubChem has increased over 80% in the past year. The PubChem staff are interested in continuing to improve the usability and accessibility of this information to the laboratory community. To this end, representatives of the ACS Divisions of Chemical Information (CINF) and Chemical Health and Safety (CHAS) are working with the PubChem staff to identify additional sources and uses for health and safety data. Efforts are also underway to improve annotation of the data and enable more specific data retrieval options. We welcome ideas for organization and presentation of the data. To participate or provide comments, contact the CINF safety representative, Leah McEwen at firstname.lastname@example.org or the CHAS secretary, Ralph Stuart at email@example.com.
Laboratory use cases for chemical safety information
Risk assessment and crisis management in the research laboratory using online resources: A EH&S perspective
UCal Chemicals: An overview of growing challenges
Chris Jakober, Russell Vernon, Phillip Painter
GHS and NFPA diamonds: How they can be useful
iRAMP & PubChem
Chemical Classification ClassyFire Applications in EHS
Surveying the chem safety landscape
Related CHED and CINF presentations:
Co-developing lab safety and chemical information skills
Ralph Stuart and Leah McEwen
Wednesday’s presentations on Chemical, Sample & Asset Management Tools discussed a variety of aspects of how the safety program collects, organizes and uses data and information related to chemicals and their hazards. The morning’s presentations focused on chemical inventories: why institutions need them; some platforms for collecting and reporting the information associated with them; and what they look like “on the ground”.
The afternoon presentations took a more global approach to chemical safety information in the lab, discussing the organizational, environmental and information contexts of this data. The last speaker of the day described an emerging innovative approach to collecting “Lessons Learned” information from laboratory events,
Chemical inventories: What are they good for? R. Stuart
How UNHCEMS has evolved from a Chemical Inventory Tracking system to an Environmental Management Tool. C. Myer, P. Collins, A. Glode
Use of RFID and scanning technologies for managing large Chemical Inventories. J.M. Pickel 10:25: Intermission.
Developing a cloud based chemical inventory application for the University of California System (UC Chemicals). H. Weizman
Using a chemical inventory system to optimize safe laboratory research. G. Baysinger, R. Creed, L.M. Gibbs
Chemical stockroom management: Lessons learned ten years in. S.B. Sigmann
PubChem’s Laboratory Chemical Safety Summary (LCSS). S. Kim, J. Zhang, A. Gindulyte, P. Thiessen, L. McEwen, R. Stuart, E. Bolton, S. Bryant
Socio-Legal Issues in the Application of Semantic Web Technology to Chemical Safety. J.G. Frey, M.I. Borkum
Symposium on Safety in the Academic Research Laboratory
SCTY 18: Safe science: Promoting a culture of safety in academic research (link to report discussed in this presentation)
SCTY 19: Safety first culture in Australian laboratories
SCTY 20: Comprehensive and effective program for environmental safety education in universities
SCTY 21: Laboratory safety in ChBE at Georgia Tech and the PALS collaboration with ExxonMobil
SCTY 22: International differences in laboratory safety preparation for chemistry graduate students
SCTY 23: Evolution of safety culture in University of California academic research laboratories
John Palmer, Lawrence Wong
SCTY 24: Laboratory Scale Risk Assessment
SCTY 25: Study of students’ engagement in various styles of safety videos
SCTY 46: From accident analysis to accident prevention at UCLA
SCTY 47: A student’s perspective on safety in the academic lab
SCTY 48: Assessment and management of chemical risks in academic laboratories: (1) Important factors for risk assessment in chemical laboratories
SCTY 49: Advancing safety culture in academic research laboratories: A case study (link to the study discussed in this presentation)
2:00pm-2:20pm Tue, Dec 15 Lawrence Gibbs
SCTY 50: Assessment and management of chemical risks in academic laboratories (2) Influence of laboratory layout on airflow in university laboratory
SCTY 51: Assessment and management of chemical risks in academic laboratories (3) Oshima et al – Observing behavior of experimenter and chemical
SCTY 52: Ensuring a safe and successful research laboratory for deaf and hard-of-hearing undergraduate students
SCTY 55: Leveraging academic safety culture as a value-added tool for maximizing the undergraduate research experience and Introducing general chemistry students to academic safety culture through participatory case study development Gregory Ferrence
Current Topics in Chemical Safety Information
Cosponsored by the Committee on Chemical Safety, Division of Chemical Education and Division of Chemical Information